Otovia Therapeutics

Company news

2023.03.28

Company news

Research Achievements from the Team of Professor Renjie Chai Won the 2022 Chinese Medical Science and Technology Award


The Chinese Medical Association released the project list of 2022 Chinese Medical Science and Technology Award on March 24. In the list, the project "Research on the Treatment of Sensorineural Deafness Through Programmed Cochlear Implantation and Hair Cell Regeneration" completed by Professor Renjie Chai et al. from the Department of Otolaryngology-Head and Neck Surgery, Zhongda Hospital, Southeast University won the second prize.


Professor Renjie Chai (Executive Dean of the Advanced Institute of Life and Health of Southeast University, Double-Employed Professor of Zhongda Hospital, Southeast University, and Professor of Otolaryngology-Head and Neck Surgery of Zhongda Hospital) denoted that the prevention and treatment of deafness are major national strategic needs for the lives and health of Chinese people. Deafness is mainly induced by the irreversible loss of hair cells and auditory neurons. For the treatment of sensorineural deafness as a major strategic need in China, over 30 high-quality papers in three categories have been published in Cell and other periodicals, and more than 10 invention patents have been applied in this project. In the project, the regeneration of functional auditory neurons was realized by synergistic regulation of neural stem cells via physical and biological factors, creating a novel comprehensive technical system combining with neural stem cell transplantation and cochlear implantation. Meanwhile, the cochlear implantation process was optimized for a new programmed cochlear implantation technology. Besides, a gene therapy system for stem cells in inner ear was constructed, through which hair cell regeneration was boosted. The original achievement published in Cell was rated as the best paper of the year by this formal periodical, which, among the nine best papers in Cell, was the only one completely independently accomplished by Chinese scholars, and was also selected as the top 30 candidate progresses of China's top ten scientific advances in the year screened by the Ministry of Science and Technology of the People's Republic of China. The research achievement has laid a theoretical and practical foundation for the treatment of sensorineural deafness, which has not only been popularized and applied in over ten 3A hospitals like Nanjing Drum Tower Hospital, but also attracted the attention and investment of the pharmaceutical industry, resulting in good social and economic benefits.


It is reported that as one of the 26 awards established by the first batch of social forces in China and approved by the Ministry of Health and the Ministry of Science and Technology of the People's Republic of China, the Chinese Medical Science and Technology Award consists of the Medical Science and Technology Award, the International Science and Technology Cooperation Award, the Health Management Award, the Medical Science and Technology Popularization Award, the Health Policy Award, and the Youth Science and Technology Award. It is a science and technology award established by the Chinese Medical Association for the national medical and health filed. It functions positively in enhancing the innovation and level of medical science and technology in China and popularizing advanced medical science and technology. The Chinese Medical Science and Technology Award aims to reward individuals who have made outstanding contributions to the field of medical science and technology. The 2022 Chinese Medical Science and Technology Award was reviewed by experts of the Chinese Medical Science and Technology Award Review Committee and submitted to the 8th meeting of the 26th Council of the Chinese Medical Association for deliberation and confirmation. Totally eighty projects were awarded the 2022 Chinese Medical Science and Technology Award, including 8 first prizes, 24 second prizes and 48 third prizes. (Min Liu and Shouqin Cheng)